Review Article | 25 Nov 2022

A review of some medicinal plants with the potential to defeat antimicrobial resistance: Cases of Benin, Togo, Ghana, Burkina Faso, and Cape Verde

Victorien Dougnon1, Boris Brice Legba1, Bertin Gbaguidi1, Eric Agbodjento1, Alidehou Jerrold Agbankpe1, Diara Rocha2, Irene Ayi3, Simon Azonbakin1, Aboudoulatif Diallo4, Isidore Juste Bonkoungou5, Jean Robert Klotoe1, Clément Agbangla1, and Guy Alain Alitonou1Show more
1. Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
2. Department of Biology, University of Cape Verde, Cape Verde.
3. Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Ghana.
4. Department of Pharmacy, Faculty of Health Science, University of Lome, Togo.
5. Department of Biochemistry - Microbiology, University of University Joseph KI ZERBO, Burkina-Faso.

Corresponding author: Victorien Dougnon (victorien.dougnon@gmail.com)

Received: 03-07-2022, Accepted: 14-10-2022, Published: 25-11-2022

INTERNATIONAL JOURNAL OF ONE HEALTH | pg no. 124-160 | Vol. 8, Issue 1 | DOI: 10.14202/IJOH.2022.124-160
Citations: —
View PDF

Cite this Article

  • APA
  • MLA
  • Chicago
  • Vancouver
  • Harvard

                    
                  

                

              

            


            



            
            

          

            
Abstract

              
Background and Aim: Antimicrobial resistance (AMR) is a global public health problem. In the alternatives being explored for developing new antimicrobials, medicinal plants occupy an important place, particularly in Africa, where they are widely used. This review aims to analyze the potential of medicinal plants from Benin, Togo, Ghana, Burkina-Faso, and Cape Verde in the fight against AMR. A bibliographic search was conducted to explore scientific databases such as PubMed and Google Scholar. During this search, particular attention was given to epidemiological data related to AMR in these countries, medicinal plants traditionally used to treat microbial infections and medicinal plants that have been shown to be active on multidrug-resistant microbial strains. In total, 94 manuscripts were investigated. Epidemiological data showed that the problem of AMR is worsening in each target country. In addition, several medicinal plants have been demonstrated to be effective against microbial strains resistant to conventional antibiotics. A total of 532 medicinal plants were identified according to their ethnomedical uses for the treatment of microbial infections. Scientific evidence was collected on the antimicrobial potential of 91 plants. This study showed the potential of medicinal plants in the fight against AMR. Their documented traditional use, coupled with the evidence of efficacy provided, make them interesting sources for developing new antimicrobials.

             
Keywords: Africa, antimicrobial, drug resistance, medicinal plants.