Review (Published online: 25-11-2022)
6. A review of some medicinal plants with the potential to defeat antimicrobial resistance: Cases of Benin, Togo, Ghana, Burkina Faso, and Cape Verde
Victorien Dougnon, Boris Brice Legba, Bertin Gbaguidi, Eric Agbodjento, Alidehou Jerrold Agbankpe, Diara Rocha, Irene Ayi, Simon Azonbakin, Aboudoulatif Diallo, Isidore Juste Bonkoungou, Jean Robert Klotoe, Clément Agbangla, and Guy Alain Alitonou
International Journal of One Health, 8(2): 124-160
Victorien Dougnon: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Boris Brice Legba: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Bertin Gbaguidi: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Eric Agbodjento: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Alidehou Jerrold Agbankpe: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Diara Rocha: Department of Biology, University of Cape Verde, Cape Verde.
Irene Ayi: Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Ghana.
Simon Azonbakin: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Aboudoulatif Diallo: Department of Pharmacy, Faculty of Health Science, University of Lome, Togo.
Isidore Juste Bonkoungou: Department of Biochemistry - Microbiology, University of University Joseph KI ZERBO, Burkina-Faso.
Jean Robert Klotoe: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Clément Agbangla: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
Guy Alain Alitonou: Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Benin.
doi: www.doi.org/10.14202/IJOH.2022.124-160
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Article history: Received: 03-07-2022, Accepted: 14-10-2022, Published online: 25-11-2022
Corresponding author: Victorien Dougnon
E-mail: victorien.dougnon@gmail.com
Citation: Dougnon V, Legba BB, Gbaguidi B, Agbodjento E, Agbankpe AJ, Rocha D, Ayi I, Azonbakin S, Diallo A, Bonkoungou IJ, Klotoe JR, Agbangla C, and Alitonou GA (2022) A review of some medicinal plants with the potential to defeat antimicrobial resistance: Cases of Benin, Togo, Ghana, Burkina Faso, and Cape Verde, Int. J. One Health, 8(2):124–160.
Antimicrobial resistance (AMR) is a global public health problem. In the alternatives being explored for developing new antimicrobials, medicinal plants occupy an important place, particularly in Africa, where they are widely used. This review aims to analyze the potential of medicinal plants from Benin, Togo, Ghana, Burkina-Faso, and Cape Verde in the fight against AMR. A bibliographic search was conducted to explore scientific databases such as PubMed and Google Scholar. During this search, particular attention was given to epidemiological data related to AMR in these countries, medicinal plants traditionally used to treat microbial infections and medicinal plants that have been shown to be active on multidrug-resistant microbial strains. In total, 94 manuscripts were investigated. Epidemiological data showed that the problem of AMR is worsening in each target country. In addition, several medicinal plants have been demonstrated to be effective against microbial strains resistant to conventional antibiotics. A total of 532 medicinal plants were identified according to their ethnomedical uses for the treatment of microbial infections. Scientific evidence was collected on the antimicrobial potential of 91 plants. This study showed the potential of medicinal plants in the fight against AMR. Their documented traditional use, coupled with the evidence of efficacy provided, make them interesting sources for developing new antimicrobials.